Illustration created for an article describing a study conducted by NUS researchers. Mycobacterium abscessus causes lung infection in vulnerable population and is very difficult to treat using the existing combinations of antimicrobial agents due to its unusually thick and complex mycobacterial envelope.
Illustration created for an article describing a study conducted by NUS researchers. The novel compound COE-PNH2, a conjugated oligoelectrolyte (COE) with cationic side groups is a small amphiphilic molecule with both hydrophilic and hydrophobic portions.
Illustration created for an article describing a study conducted by NUS researchers. COE-PNH2 triggers ATP depletion, mycomembrane disruption and abnormal plasma membrane structures in Mycobacterium abscessus.
