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An illustration for an article describing a study conducted by NUS researchers. neuropeptides are short peptide chains produced by neurons, and can bind receptors to trigger physiological effects.
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An illustration for an article describing a study conducted by NUS researchers. A neuropeptide Relaxin-3 binds a receptor RXFP3 to trigger ERK1/2 signalling and cause desensitisation. However, when a fragment of the neuropeptide was modified by 'stapling', the RXFP3 signalling was altered.